Liposomal Technology

Liposomes are essentially used to incorporate and carry active ingredients of very different types and for very different applications, with the aim of improving their therapeutic properties, primarily their efficacy and safety.

Liposomes are nanoscale vesicles composed mainly of phospholipids arranged in bilayers. These vesicles contain an internal aqueous phase and are suspended in an external aqueous phase.

Their nanoscale and physical and chemical characteristics, similar to those of biological membranes, allow the structures to circulate around the body, carrying and releasing the encapsulated active ingredient in a controlled way that is different from that of conventional pharmaceutical formulations.

Enoc Pharma bases the activity of all its products on the most advanced liposomal technology, Advanced Liposomes.

What liposomes bring to active ingredients
  • More selective transport.
  • Increased efficacy.
  • Reduced toxicity and side effects.
  • Stabilization, both ‘in vitro’ and ‘in vivo’.
  • Better absorption, penetration and dissemination in the body.
  • Control over the time of release and duration of the treatment, which can be prolonged or modulated.
  • Option of using alternative administration routes.
  • Possibility of combining different active ingredients in the same liposome.
  • Possibility of combining different liposomes in the same formulation (SDS system).
Characteristics of Advanced Liposomes
  • Very high quality liposomes (pharmaceutical standard).
  • Unilamellar.
  • Uniform, stable particle size.
  • Particle diameter of between 50 and 200 nm, depending on the active ingredient and the lipid mix used. Can be sterile filtered.
  • High physical and chemical stability of the particle and active ingredient, whether ‘in vitro’ or ‘in vivo’.
  • Excellent adaptation to environments with other polarities, to ionic and osmotic changes, and to pH variations.
  • Very long circulation time (‘Stealth’ liposomes).
  • Possibility of adapting the characteristics of the membrane to the desired function. Control of permeability and the fusion capacity of the liposomes.
  • Possibility of administering them via every route used in medicine. Integral absorption of the liposomes in all administration routes.
  • Integral passage of the liposomes through the blood-brain, gastrointestinal, cutaneous and other barriers.
  • Possibility of very specific targeting. Anchoring of monoclonal antibodies to the liposomal surface.
  • Possibility of using empty liposomes for the extemporaneous encapsulation of active ingredients.
  • Excellent biocompatibility. Can be fully bio-assimilated. Zero toxicity.
  • Wide range of uses in the fields of health, personal care and industry in general.